Hawking was a generous charitable sponsor and donor, who set up the Stephen Hawking Foundation "to facilitate research into Cosmology, Astrophysics and Fundamental Particle Physics both at school and university level" and also "facilitate and support work relating to Motor Neurone Disease and those living with the disease".
"My advice to other disabled people is to concentrate on things your disability doesn't prevent you from doing well and don't regret the things it interferes with".
Hawking has made many important contributions to the fields of cosmology and quantum gravity.
His longtime academic home, the University of Cambridge, shared a touching video tribute narrated by Hawking.
British physicist and Professor Brian Cox called him "one of the greats" saying physicists in 1,000 years' time "will still be talking about Hawking radiation", his theory about black holes.
Stephen William Hawking will live on forever as one of the brightest and most profound scientists to grace the scientific fraternity.
Hawking's efforts to make science accessible to the public saw him appear as himself on many television shows including the science-fiction series "Red Dwarf" and "Star Trek: The Next Generation", he also portrayed himself on the animated shows "The Simpsons" and "Futurama".
Hawking published A Brief History of Time in 1988.
Prof Hawking arrived at the university in 1962 as a PhD student, and was eventually given the prestigious title of Lucasian Professor of Mathematics, a position once held by Sir Isaac Newton, in 1979.
Professor Stephen Hawking was delighted when Eddie Redmayne won an Oscar for portraying him in the film The Theory Of Everything.
"I think the human race has no future if it doesn't go into space", he said.
"We are each free to believe what we want, and it's my view that the simplest explanation is; there is no god".
When he turned 75 in January of a year ago, Hawking shared his surprise that he had made it that far in life and left us with a quote about black holes that might as well serve as an encouraging metaphor for life in the political darkness that is 2018.
He has published many books, including global best seller A Brief History of Time. During a 2016 interview with ITV's Good Morning Britain, he was quite blunt when questioned about Donald Trump's growing appeal ahead of the U.S, presidential election.
Stephen Hawking will be remembered as the "Master of the Universe" but some might be surprised to know that the physicist left a lasting legacy in South Africa.
His life was also portrayed in an Academy Award nominated film titled "The Theory of Everything" which was based on a memoir by his wife Jane Hawking.
He is survived by his children Lucy, Robert and Tim who released a heartfelt statement about their father's death. In 1995 he marries his former nurse, Elaine Mason; they too divorce after several years. "He is a demagogue who seems to appeal to the lowest common denominator", Hawking said.