The use of oral antibiotics is associated with an increased risk of developing kidney stones, according to a United States scientific study that makes such a correlation for the first time. These risks were more visible in children and adolescents. The condition is, however, associated with bacterial changes in the intestines and urinary tract, leading investigators to study the relationship between antibiotics and kidney stones. Antibiotics, prescribed more often in children, may play a role in this increase.
For reasons that are not clear, nephrolithiasis (kidney stone) has increased by about 70% over the past 30 years, especially among children and adolescents, according to the Athens News Agency.
A groundbreaking new study is the first to link the use of antibiotics to kidney stones.
Kidney stones are pebble-like mineral deposits that can form in either or both of the kidneys. Young people also seemed to be most susceptible to developing kidney stones after taking these medications, they add.
"Everyone thinks you're older when you get them, so no one believed it when I said I had kidney stones", said Gaal. Just because children are prescribed more of them as compared to adults, researchers suggest that the clinicians need to be more honest and mindful while prescribing medication especially when they are dealing with young patients.
The data included the treatment history of 26,000 individuals with kidney stones, which the team compared with the health records of nearly 260,000 people who had not developed kidney stones (the controls). Around 30 percent of the prescribed antibiotic files are not the right medication according to Tasian.
Results Exposure to any of five different antibiotic classes 3-12 months before index date was associated with nephrolithiasis. "Our findings suggest that antibiotic prescription practices represent a modifiable risk factor, a change in prescribing patterns might decrease the current epidemic of kidney stones in children", Tasian noted.
Tasian and his colleagues are hoping to expand this research into broader, population-based studies to better understand how variations in microbiome composition may influence the development of kidney stones.