The Keep Antibiotics Working campaign advocates inhabitants in South West to continually have faith in their doctor, nurse or pharmacist's guidance as per their requirement for antibiotics if they are prescribed, consume antibiotics as administered and never store them for eventual use or split them with others.
Public Health England, which has launched a campaign called Keep Antibiotics Working, says that antibiotics are not essential for every illness and patients should not go to their doctors expecting such medication.
With few new drugs in development, Dame Sally Davies, chief medical officer for England, has warned of a "post-antibiotic..."
Since the Government first launched its five-year antimicrobial resistance strategy in 2013, Global Positioning System have issued around 2.5million fewer antibiotic prescriptions - dropping by 13 percent from the peak in 2014.
The new campaign tells people to always trust their doctor, nurse or pharmacist on when to take antibiotics.
"The fact is if you take an antibiotic when you don't need it then you're more likely to have an infection that the antibiotics don't work for over the coming months".
"We need to get to a stage where antibiotics are not seen as a "catch all" for every illness - and patients need to understand that if their doctor does not prescribe antibiotics, it is because they genuinely believe that they are not the most appropriate treatment". Reducing inappropriate use can help us stay ahead of superbugs'. The public has a critical role to play and can help by taking collective action.
Mrs Mead said: "I think it's right that we don't use antibiotics flippantly".
Antibiotics are crucial to cover significant infections such as meningitis, pneumonia and sepsis.
Finally, I would like to thank you for your support in tackling this important issue, and for your work in preserving the effectiveness of antibiotics for our future generations. "It was clinically evident he needed them".
Prof Neil Woodford, head of antimicrobial resistance at PHE's laboraties in North London, said the most potent antibiotics, like carbapenems, were failing more often than other less potent antibiotics.
"Taking antibiotics when you don't need them puts you and your family at risk of developing infections which in turn can not be easily treated with antibiotics". If patients don't stop demanding antibiotics, experts fear that infections will kill more people than cancer by 2050.
'Without urgent action from all of us, common infections, minor injuries and routine operations will become much riskier'.
Health Minister Steve Brine said: "This Government is firmly committed to combating drug-resistant infections and refuses to allow modern medicine to grind to a halt - simple steps can make a huge difference".
"The temptation to lobby for antibiotics can be overwhelming, so this Public Health England advice is welcome".